This article explores research examining whether the proportion of chromosomally normal embryos varies across different IVF clinics — and what this means for patients choosing where to undergo treatment. The full content of this article is available on request.
Research published in Human Reproduction analyzed 1,645 egg donor cycles and 13,282 blastocyst biopsies across 42 US fertility clinics, all using the same PGS laboratory and technology to eliminate method-related variables. The findings were striking: the average rate of euploid (chromosomally normal) embryos ranged from 39.5% to 82.5% across different centers.
While the retrospective nature of the study prevents definitive causal claims, the magnitude of the difference strongly suggests that both laboratory practices and physician-directed ovarian stimulation protocols significantly impact results — factors that vary considerably from clinic to clinic.
Despite surface similarities between programs, deeper evaluation reveals substantial differences that warrant careful investigation before selecting a fertility center for treatment.
When choosing a fertility clinic, patients should ask not only about overall success rates but specifically about blastocyst development rates, stimulation protocols, and embryo laboratory practices — because these factors directly influence the quality of embryos available for transfer.
