IVF and Twins: Why Single Embryo Transfer Is Safer

This myth is one of the most common misconceptions about IVF. The American Society for Reproductive Medicine (ASRM) specifically identified it as a myth worth correcting.

The Myth

“IVF always results in twins and triplets.”

The Facts

It is true that IVF treatment historically increased the risk of multiple births — mostly due to the transfer of more than one embryo. However, recent advances in assisted reproductive technology have dramatically improved the odds of success with the transfer of only one embryo.

It is important to choose your reproductive health specialist carefully by asking questions about success rates in achieving pregnancy while avoiding multiple births — which can be accompanied by greater health risks.

At CEGYR, we have consistently advocated for single embryo transfer (eSET) when clinically appropriate. Blastocyst-stage transfers, combined with PGT-A testing where indicated, have enabled us to achieve excellent success rates while dramatically reducing the incidence of multiple pregnancies. A singleton pregnancy is a safer pregnancy — for both mother and baby.

Multiple pregnancies carry elevated risks of preterm birth, low birth weight, gestational diabetes, preeclampsia, and other complications. Reducing multiple births is not just a preference — it is a patient safety priority.

Dr. Demián Glujovsky

Written by
Scientific Director at CEGYR, Argentina’s first reproductive medicine center. Cochrane editor and reviewer, 50+ peer-reviewed publications, trained at Columbia University NY and RMA New Jersey.